SCHEMBL7915020 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	ACACB	O00763	8/20	0.42

▸	BRD4	O60885	1/20	0.37

▸	CREBBP	Q92793	1/20	0.37

▸	MCHR1	Q99705	6/20	0.37

▸	ADRB1	P08588	1/20	0.34

▸	CYP2D6	P10635	1/20	0.34

▸	MEN1	O00255	1/20	0.34

▸	LMNA	P02545	1/20	0.34

▸	CYP1A2	P05177	1/20	0.34

▸	CYP2C9	P11712	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

▸	ACACA	Q13085	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12432861	1.00	ACACB (0.42)	ACACBBRD4CREBBPMCHR1ADRB1
SCHEMBL1391850	0.85	ACACB (0.52)	ACACBACACA
SCHEMBL1391021	0.85	ACACB (0.52)	ACACBACACA
SCHEMBL1391157	0.85	ACACB (0.52)	ACACBACACA
SCHEMBL1391411	0.85	ACACB (0.52)	ACACBACACA
SCHEMBL7921645	0.78	BRD4 (0.50)	ACACBBRD4CREBBPMCHR1
SCHEMBL1390761	0.75	ACACA (0.55)	ACACBACACA
SCHEMBL7921328	0.73	ACACB (0.49)	ACACBACACA
SCHEMBL12433361	0.73	ACACB (0.49)	ACACBACACA
SCHEMBL12433362	0.73	ACACB (0.45)	ACACBMCHR1ACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010050445-A1	BICYCLIC COMPOUND	武田薬品工業株式会社 (JP)	2010-05-06	—	—	WO	disclosed