Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12433362 | 0.78 | ACACB (0.45) | MCHR1ACACBFFAR1 | |
| SCHEMBL7915020 | 0.78 | ACACB (0.42) | BRD4CREBBPMCHR1ACACB | |
| SCHEMBL12432861 | 0.78 | ACACB (0.42) | BRD4CREBBPMCHR1ACACB | |
| SCHEMBL1391157 | 0.77 | ACACB (0.52) | ACACB | |
| SCHEMBL1391021 | 0.77 | ACACB (0.52) | ACACB | |
| SCHEMBL1391411 | 0.77 | ACACB (0.52) | ACACB | |
| SCHEMBL1391850 | 0.77 | ACACB (0.52) | ACACB | |
| SCHEMBL13799418 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1TDP1 | |
| SCHEMBL8268612 | 0.72 | KCNJ1 (0.39) | KDM4EALDH1A1TDP1 | |
| SCHEMBL28072390 | 0.70 | LTA4H (0.49) | PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |