Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391021 | 0.80 | ACACB (0.52) | ACACBACACA | |
| SCHEMBL1391850 | 0.80 | ACACB (0.52) | ACACBACACA | |
| SCHEMBL1391157 | 0.80 | ACACB (0.52) | ACACBACACA | |
| SCHEMBL1391411 | 0.80 | ACACB (0.52) | ACACBACACA | |
| SCHEMBL7921645 | 0.78 | BRD4 (0.50) | ACACBMCHR1FFAR1 | |
| SCHEMBL7915020 | 0.73 | ACACB (0.42) | ACACBMCHR1ACACA | |
| SCHEMBL12432861 | 0.73 | ACACB (0.42) | ACACBMCHR1ACACA | |
| SCHEMBL1390761 | 0.70 | ACACA (0.55) | ACACBACACA | |
| SCHEMBL1390554 | 0.69 | ACACB (0.45) | ACACBMTNR1AACACAFFAR1 | |
| SCHEMBL17753764 | 0.69 | MTNR1A (0.65) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351743-A1 | BICYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-08-03 | — | — | EP | disclosed |