Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923139 | 0.95 | MEN1 (0.53) | MEN1KMT2ATSHRTACR1DRD2 | |
| SCHEMBL7923414 | 0.90 | MEN1 (0.54) | MEN1KMT2ATSHRTACR1DRD2 | |
| SCHEMBL7921529 | 0.90 | LMNA (0.55) | MEN1KMT2ATSHRTACR1DRD3 | |
| SCHEMBL7921904 | 0.88 | MEN1 (0.48) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7927130 | 0.88 | MEN1 (0.54) | MEN1KMT2ATSHRTACR1DRD2 | |
| SCHEMBL7924011 | 0.87 | KDM4E (0.46) | TSHRDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL7921522 | 0.85 | KMT2A (0.56) | MEN1KMT2ATSHRTACR1ALDH1A1 | |
| SCHEMBL7923134 | 0.85 | KDM4E (0.53) | KMT2ATSHRDRD2DRD4DRD3 | |
| SCHEMBL7915565 | 0.84 | LMNA (0.56) | MEN1KMT2ATSHRTACR1DRD2 | |
| SCHEMBL7924082 | 0.83 | MEN1 (0.48) | MEN1KMT2AALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |