Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924082 | 0.95 | MEN1 (0.48) | MEN1KMT2APOLBKDM4EHTR1A | |
| SCHEMBL7927349 | 0.91 | MEN1 (0.50) | MEN1KMT2APOLBKDM4EHTR1A | |
| SCHEMBL7924050 | 0.89 | MEN1 (0.50) | MEN1KMT2APOLBHTR1ASIGMAR1 | |
| SCHEMBL7915262 | 0.88 | MEN1 (0.52) | MEN1KMT2APOLBKDM4ESIGMAR1 | |
| SCHEMBL7927378 | 0.87 | MEN1 (0.60) | MEN1KMT2APOLBCCR3 | |
| SCHEMBL7927354 | 0.83 | KCNH2 (0.49) | MEN1KMT2AKCNH2CCR3ALDH1A1 | |
| SCHEMBL7923139 | 0.83 | MEN1 (0.53) | MEN1KMT2APOLBKDM4EHTR1A | |
| SCHEMBL7921529 | 0.82 | LMNA (0.55) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7924032 | 0.81 | MEN1 (0.51) | MEN1KMT2APOLBKDM4EHTR1A | |
| SCHEMBL7923414 | 0.79 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |