Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921529 | 0.95 | LMNA (0.55) | LMNAALDH1A1TSHRTP53RECQL | |
| SCHEMBL7921573 | 0.92 | LMNA (0.58) | LMNAALDH1A1TSHRTP53RECQL | |
| SCHEMBL7915494 | 0.91 | LMNA (0.45) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7923527 | 0.90 | TP53 (0.47) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921580 | 0.90 | LMNA (0.45) | LMNAALDH1A1TSHRTP53NPSR1 | |
| SCHEMBL7923139 | 0.89 | MEN1 (0.53) | LMNAALDH1A1TSHRTP53MEN1 | |
| SCHEMBL7921616 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRTP53NPSR1 | |
| SCHEMBL7921790 | 0.89 | DRD2 (0.46) | LMNAALDH1A1TSHRTP53NPSR1 | |
| SCHEMBL6139831 | 0.88 | LMNA (0.56) | LMNAALDH1A1TSHRTP53RECQL | |
| SCHEMBL7923519 | 0.87 | LMNA (0.61) | LMNAALDH1A1TSHRTP53RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |