SCHEMBL414254

SCHEMBL414254

O=[N+]([O-])c1cc([N+](=O)[O-])c2ccccc2c1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.54
HPRT1 P00492 1/20 0.53
CTSB P07858 3/20 0.51
SIRT2 Q8IXJ6 1/20 0.51
TSHR P16473 2/20 0.50
GPR35 Q9HC97 1/20 0.50
ALDH1A1 P00352 6/20 0.47
MAPT P10636 5/20 0.45
HPGD P15428 3/20 0.45
KDM4E B2RXH2 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
HTT P42858 3/20 0.45
GAA P10253 1/20 0.45
IDO1 P14902 1/20 0.45
TDO2 P48775 1/20 0.45
NPC1 O15118 1/20 0.45
S1PR4 O95977 1/20 0.45
S1PR1 P21453 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378223 1.00 TDP1 (0.54) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL15302617 0.86 TDP1 (0.50) TDP1HPRT1TSHRGPR35ALDH1A1
Chloroneb SCHEMBL23037464 0.84 LMNA (0.50) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL11422864 0.79 CDK2 (0.52) TSHRGPR35ALDH1A1MAPTHPGD
SCHEMBL6245129 0.79 HPRT1 (0.78) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL7827176 0.77 CASP6 (0.59) TDP1HPRT1CTSBTSHRGPR35
SCHEMBL9342506 0.77 LMNA (0.42) TDP1CTSBGPR35ALDH1A1MAPT
SCHEMBL12712555 0.76 TDP1 (0.54) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL5624830 0.76 TDP1 (0.54) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL8807367 0.76 TDP1 (0.54) TDP1HPRT1CTSBSIRT2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2775842-B1 1-substituted-5-fluoro-3,6-dihydro-6-imino-2(1H)-pyrimidinone derivatives as fungicidal agents for use in plant protection ADAMA MAKHTESHIM LTD (IL) 2017-10-04 EP claimed
CN-103874413-B 5-fluoro-4-imino-3- (substituted) -3, 4-dihydropyrimidin-2 (1H) one derivatives 阿达玛马克西姆股份有限公司 2017-03-08 CN claimed
US-7795456-B2 Insecticidal N-substituted sulfoximines DOW AGROSCIENCES LLC (US) 2010-09-14 US claimed
WO-2026101906-A1 MIXTURES FOR FUNGAL CONTROL IN CORN CORTEVA AGRISCIENCE LLC (US) 2026-05-15 WO disclosed
WO-2026101908-A1 MIXTURES FOR FUNGAL CONTROL IN SOYBEANS CORTEVA AGRISCIENCE LLC (US) 2026-05-15 WO disclosed
WO-2026101907-A1 MIXTURES FOR FUNGAL CONTROL IN CEREALS CORTEVA AGRISCIENCE LLC (US) 2026-05-15 WO disclosed
US-12616081-B2 High precision greenhouse seed and seedling treatment SYNGENTA CROP PROTECTION AG (CH) 2026-05-05 US disclosed
US-20260117244-A1 INHIBITORY RNA FOR THE CONTROL OF PHYTOPATHOGENS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-30 US disclosed
US-12590317-B2 Polynucleotides and methods for transferring resistance to Asian soybean rust PIONEER HI-BRED INTERNATIONAL, INC. (US) 2026-03-31 US disclosed
US-12575573-B2 Methods of using a colloidal silver-based composition in reducing or preventing microbial contamination in plants or explants in tissue culture processes Clearleaf Inc. (US) 2026-03-17 US disclosed
US-12490744-B2 Methods of use of seed-origin endophyte populations INDIGO AG, INC. (US) 2025-12-09 US disclosed
EP-0263984-A2 Imaging element containing dye masking coupler EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-04-20 EP disclosed
US-4482759-A Fungicidally active benzhydrol derivatives DEGUSSA AKTIENGESELLSCHAFT (DE) 1984-11-13 US disclosed
US-4324799-A Fungicidal thioglycolic acid anilides, processes for their manufacture and pesticidal compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4293566-A FUNGICIDES, BACTERICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed
EP-0023332-A2 Fungicidal thioglycolic acid anilides, process for their preparation and pesticides containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-04 EP disclosed
US-4214907-A Photosensitive material for electrophotography having a polyvinyl carbazole derivative, phthalocyanine, and an electron-acceptor MITA INDUSTRIAL COMPANY, LTD. (JP) 1980-07-29 US disclosed
US-4183949-A Pesticidally active 1-arylamino-2,4-dinitronaphthalenes BAYER AKTIENGESELLSCHAFT (DE) 1980-01-15 US disclosed
US-3980798-A Dichloromaleic imides for fungicidal composition and method CIBA-GEIGY CORPORATION (US) 1976-09-14 US disclosed
US-3932509-A FUNGICIDES, VIRICIDES CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616081-B2 High precision greenhouse seed and seedling treatment DCX, MYB, CROCC TDP1 3774/4885HPRT1 2864/4885CTSB 2896/4885
US-20260117244-A1 INHIBITORY RNA FOR THE CONTROL OF PHYTOPATHOGENS ATG13, MAVS, ATG7 TDP1 2748/4885HPRT1 2415/4885CTSB 1834/4885
US-12575573-B2 Methods of using a colloidal silver-based composition in reducing or preventing microbial contamination in plants or explants in tissue culture processes ALG1, MYB, CHIT1 TDP1 1650/4885HPRT1 3513/4885CTSB 3746/4885
US-12590317-B2 Polynucleotides and methods for transferring resistance to Asian soybean rust SRRT, PHAX, ERN2 TDP1 2158/4885HPRT1 953/4885CTSB 3993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.