Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | DRD4 | P21917 | 5/20 | 0.51 |
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924075 | 0.92 | KDM4E (0.47) | DRD2DRD4DRD3ALDH1A1TSHR | |
| SCHEMBL7924011 | 0.91 | KDM4E (0.46) | DRD2DRD4DRD3ALDH1A1TSHR | |
| SCHEMBL7927315 | 0.90 | KDM4E (0.58) | DRD2DRD4DRD3ALDH1A1TSHR | |
| SCHEMBL7915448 | 0.89 | KDM4E (0.46) | DRD2DRD4DRD3ALDH1A1TSHR | |
| SCHEMBL7921573 | 0.86 | LMNA (0.58) | DRD2DRD4DRD3ALDH1A1TSHR | |
| SCHEMBL7923414 | 0.86 | MEN1 (0.54) | DRD2DRD4DRD3ALDH1A1TSHR | |
| SCHEMBL7922874 | 0.85 | MAPT (0.44) | DRD2DRD4DRD3ALDH1A1TSHR | |
| SCHEMBL7921984 | 0.83 | ALDH1A1 (0.57) | DRD4DRD3ALDH1A1TSHRKDM4E | |
| SCHEMBL7927375 | 0.82 | KDM4E (0.54) | DRD2DRD4DRD3ALDH1A1TSHR | |
| SCHEMBL7924162 | 0.82 | KDM4E (0.62) | DRD2DRD4DRD3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |