Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD4 | P21917 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915440 | 0.85 | DRD2 (0.51) | MAPTKDM4EDRD2DRD4DRD3 | |
| SCHEMBL7924027 | 0.84 | LMNA (0.48) | MAPTKDM4EDRD2DRD4ALDH1A1 | |
| SCHEMBL7924150 | 0.83 | IGF1R (0.41) | MAPTKDM4EDRD2ALDH1A1MEN1 | |
| SCHEMBL7923469 | 0.82 | IGF1R (0.41) | MAPTKDM4EDRD2ALDH1A1MEN1 | |
| SCHEMBL7923493 | 0.81 | LMNA (0.47) | MAPTKDM4EDRD2DRD4ALDH1A1 | |
| SCHEMBL7915529 | 0.80 | IGF1R (0.44) | MAPTKDM4EDRD2DRD4DRD3 | |
| SCHEMBL7921573 | 0.80 | LMNA (0.58) | MAPTKDM4EDRD2DRD4DRD3 | |
| SCHEMBL7923414 | 0.79 | MEN1 (0.54) | MAPTKDM4EDRD2DRD4DRD3 | |
| SCHEMBL7921965 | 0.79 | ABCB1 (0.43) | MAPTDRD2DRD4ALDH1A1TSHR | |
| SCHEMBL7923980 | 0.79 | SMN1; SMN2 (0.38) | MAPTKDM4EDRD2DRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |