Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | STK10 | O94804 | 3/20 | 0.45 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.45 |
| ▸ | BUB1 | O43683 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905830 | 0.82 | SIRT2 (0.48) | CNR1MEN1POLBKMT2A | |
| SCHEMBL30673072 | 0.81 | CNR1 (0.63) | CNR1STK10SLKBUB1CTSC | |
| SCHEMBL7913081 | 0.80 | HDAC3 (0.46) | CNR1BUB1PRMT6PDGFRAMAPKAPK2 | |
| SCHEMBL7914175 | 0.78 | BUB1 (0.44) | BUB1KCNH2PRMT6MEN1POLB | |
| SCHEMBL7915476 | 0.76 | CNR1 (0.45) | CNR1BUB1AURKBCYP2A6MEN1 | |
| SCHEMBL7905484 | 0.75 | MEN1 (0.50) | CNR1PRMT6AURKBCYP2A6MEN1 | |
| SCHEMBL7914160 | 0.72 | CXCR2 (0.43) | MEN1POLBKMT2AESR2 | |
| SCHEMBL7916081 | 0.71 | CNR1 (0.47) | CNR1MAPKAPK2CYP2A6BACE1KAT6A | |
| SCHEMBL17664060 | 0.71 | MAPT (0.45) | STK10SLKMEN1POLBKMT2A | |
| SCHEMBL8230052 | 0.71 | ADORA2A (0.53) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211220-B1 | ANTITUMOR AGENTS AND ANTICARCIINOGENIC AGENTS | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | claimed |
| US-6211220-B1 | ANTITUMOR AGENTS AND ANTICARCIINOGENIC AGENTS | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |
| WO-1994029277-A1 | AMILINO- OR PYRIDYLAMINO- CYCLOBUTENE- 1,2-DIONE DERIVATIVES AS cGMP PHOSPHODIESTERASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-22 | — | — | WO | disclosed |