Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924150 | 0.88 | IGF1R (0.41) | IGF1RLMNAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7923469 | 0.87 | IGF1R (0.41) | IGF1RLMNAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL2161584 | 0.87 | KDM4E (0.52) | IGF1RLMNAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7924133 | 0.86 | LMNA (0.48) | LMNAHTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL7921965 | 0.86 | ABCB1 (0.43) | IGF1RLMNAMAPTDRD2DRD4 | |
| SCHEMBL7921419 | 0.85 | LMNA (0.50) | IGF1RLMNAHTTALOX15HTR1A | |
| SCHEMBL7924162 | 0.85 | KDM4E (0.62) | LMNAHTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL7927315 | 0.82 | KDM4E (0.58) | LMNAHTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL7923519 | 0.81 | LMNA (0.61) | LMNAHTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL7922874 | 0.80 | MAPT (0.44) | LMNAKDM4ESMN1; SMN2MAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |