Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 7/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924072 | 0.88 | LMNA (0.50) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL7923524 | 0.86 | LMNA (0.48) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL7915448 | 0.86 | KDM4E (0.46) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL7921648 | 0.86 | DRD4 (0.54) | LMNATSHRDRD2DRD4MAPT | |
| SCHEMBL7924150 | 0.86 | IGF1R (0.41) | MEN1KMT2ALMNAALDH1A1DRD2 | |
| SCHEMBL6139831 | 0.86 | LMNA (0.56) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL7915529 | 0.86 | IGF1R (0.44) | LMNADRD2DRD4IGF1RMAPT | |
| SCHEMBL7927130 | 0.85 | MEN1 (0.54) | ABCB1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7923469 | 0.85 | IGF1R (0.41) | MEN1KMT2ALMNAALDH1A1DRD2 | |
| SCHEMBL7915276 | 0.81 | LMNA (0.53) | MEN1KMT2ALMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |