Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466921 | 0.90 | CNR1 (0.40) | CNR1S1PR1POLBKMT2AMEN1 | |
| SCHEMBL3466417 | 0.81 | ALDH1A1 (0.40) | CNR1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3467147 | 0.80 | ALDH1A1 (0.40) | CNR1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8024453 | 0.75 | ALDH1A1 (0.43) | POLBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL3467808 | 0.75 | PPID (0.41) | POLBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL7914919 | 0.74 | PDE4D (0.53) | CNR1POLBKMT2AMEN1MAPT | |
| SCHEMBL3467918 | 0.74 | ALDH1A1 (0.43) | POLBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL3790847 | 0.73 | PDE4D (0.68) | CNR1POLBKMT2AMEN1MAPT | |
| SCHEMBL7916008 | 0.73 | PDE4D (0.52) | CNR1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3785808 | 0.73 | PDE4D (0.52) | CNR1POLBKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |