SCHEMBL791614

SCHEMBL791614

CC(C)(C)[Si](C)(C)OCc1cc(N)cc(Br)c1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.42
AGXT P21549 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1438559 0.88 IDO1 (0.44) IDO1AGXT
SCHEMBL6490220 0.88 IDO1 (0.48) IDO1AGXT
SCHEMBL18924077 0.88 DUT (0.32)
SCHEMBL16410318 0.82 IDO1 (0.39) IDO1
SCHEMBL17615243 0.82 LOXL2 (0.30)
SCHEMBL1933709 0.82
SCHEMBL4693470 0.82 IDO1 (0.39) IDO1
SCHEMBL6301535 0.82 ALDH1A1 (0.40) IDO1
SCHEMBL15964078 0.82 IDO1 (0.39) IDO1
SCHEMBL20602566 0.81 IDO1 (0.39) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012037108-A1 AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS GLAXOSMITHKLINE LLC (US) 2012-03-22 WO disclosed