Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768447 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL8768456 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL7563709 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL23084216 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KISS1RMEN1LMNAKMT2A | |
| SCHEMBL7563707 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL15381258 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KISS1RMEN1LMNAKMT2A | |
| SCHEMBL16382874 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KISS1RMEN1LMNAKMT2A | |
| SCHEMBL25635660 | 0.78 | TAS1R3 (0.46) | FOLH1MME | |
| SCHEMBL20630558 | 0.77 | KISS1R (0.50) | ALDH1A1KISS1RMEN1LMNAKMT2A | |
| SCHEMBL13238863 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KISS1RMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048446-A2 | MODULATION OF AXON DEGENERATION | GENENTECH, INC. (US) | 2010-04-29 | — | — | WO | disclosed |