Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877985 | 0.84 | FFAR1 (0.57) | ALDH1A1MAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL11212945 | 0.79 | SMN1; SMN2 (0.58) | ALDH1A1MAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL7224442 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL11212940 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL11904034 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL74124 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL9787226 | 0.77 | MAPT (0.64) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8746689 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL8746687 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL14368887 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | disclosed |