SCHEMBL7917068

SCHEMBL7917068

N#COc1ccccc1CC[Si](Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.33
HRH1 P35367 1/20 0.32
HTR1A P08908 1/20 0.32
DRD2 P14416 1/20 0.32
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
ABCB1 P08183 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
AOC3 Q16853 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7916831 0.90 TAAR1 (0.32) TAAR1HRH1HTR1ADRD2
SCHEMBL27668716 0.83 HTR1A (0.42) TAAR1HRH1HTR1ADRD2ABCB1
SCHEMBL7906930 0.80 TAAR1 (0.42) TAAR1MTNR1AMTNR1BABCB1CYP11B1
SCHEMBL7906863 0.78 TAAR1 (0.33) TAAR1HTR1AMTNR1AMTNR1BCYP11B1
SCHEMBL1970395 0.77 TAAR1 (0.58) TAAR1MTNR1AMTNR1BABCB1SIGMAR1
SCHEMBL17060529 0.77 AR (0.46) TAAR1HTR1ASIGMAR1AOC3
SCHEMBL156947 0.75 CYP1A2 (0.37) TAAR1HRH1DRD2
SCHEMBL10701389 0.75 HTR1A (0.58) HTR1ADRD2ABCB1
SCHEMBL765987 0.74 TAAR1 (0.36) TAAR1AOC3
SCHEMBL30997335 0.74 TAAR1 (0.36) TAAR1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6217943-B1 ADHESION AND REINFORCEMENT WITH SILANE CYANATE COUPLERS 3M INNOVATIVE PROPERTIES COMPANY 2001-04-17 US disclosed
US-5912377-A CONTAINING AT LEAST ONE CYANATE ESTER GROUP AND HYDROLYZABLE SILYL GROUP; REINFORCED COMPOSITES, ADESIVES, COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-15 US disclosed
EP-0830410-B1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING & MFG (US) 1999-04-07 EP disclosed
EP-0830410-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-25 EP disclosed
WO-1996039457-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-12 WO disclosed