SCHEMBL7906930

SCHEMBL7906930

CO[Si](CCc1ccccc1OC#N)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.42
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
AOC3 Q16853 1/20 0.38
KCNH2 Q12809 1/20 0.37
HRH3 Q9Y5N1 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
ABCB1 P08183 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
IDO1 P14902 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7914933 0.91 TAAR1 (0.40) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL7906863 0.84 TAAR1 (0.33) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL1968082 0.83 TAAR1 (0.60) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL27668716 0.80 HTR1A (0.42) TAAR1SIGMAR1AOC3KCNH2HRH3
SCHEMBL7917068 0.80 TAAR1 (0.33) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL139732 0.78 TAAR1 (0.42) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL30276868 0.78 TAAR1 (0.42) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL17060529 0.78 AR (0.46) TAAR1SIGMAR1AOC3KCNH2THRB
SCHEMBL233078 0.77 ALDH1A1 (0.38) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL7913941 0.76 THRA (0.32) TAAR1MTNR1AMTNR1BTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6217943-B1 ADHESION AND REINFORCEMENT WITH SILANE CYANATE COUPLERS 3M INNOVATIVE PROPERTIES COMPANY 2001-04-17 US disclosed
US-5912377-A CONTAINING AT LEAST ONE CYANATE ESTER GROUP AND HYDROLYZABLE SILYL GROUP; REINFORCED COMPOSITES, ADESIVES, COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-15 US disclosed
EP-0830410-B1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING & MFG (US) 1999-04-07 EP disclosed
EP-0830410-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-25 EP disclosed
WO-1996039457-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-12 WO disclosed