Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 10/20 | 0.79 |
| ▸ | ABCC1 | P33527 | 6/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010707 | 0.88 | ABCB1 (0.77) | ABCB1ABCC1MAPK1MEN1KMT2A | |
| SCHEMBL7919608 | 0.87 | ABCB1 (0.78) | ABCB1ABCC1MAPK1MEN1KMT2A | |
| SCHEMBL7740995 | 0.86 | ABCB1 (0.61) | ABCB1ABCC1MAPTMAPK1NPC1 | |
| SCHEMBL20356916 | 0.86 | ABCB1 (0.79) | ABCB1ABCC1MAPTMAPK1NPC1 | |
| SCHEMBL29375530 | 0.84 | NPC1 (0.73) | ABCB1ABCC1MAPTMAPK1NPC1 | |
| SCHEMBL16179942 | 0.84 | ABCC1 (1.00) | ABCB1ABCC1 | |
| SCHEMBL6705974 | 0.82 | NPC1 (0.70) | ABCB1ABCC1MAPTMAPK1NPC1 | |
| SCHEMBL6707064 | 0.81 | MAPT (0.77) | ABCB1ABCC1MAPTMAPK1NPC1 | |
| SCHEMBL7245174 | 0.81 | NPC1 (0.76) | ABCB1ABCC1MAPTMAPK1NPC1 | |
| SCHEMBL8777925 | 0.80 | ABCB1 (0.71) | ABCB1ABCC1MAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211177-B1 | SIDE EFFECT REDUCTION | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |