SCHEMBL7917792

SCHEMBL7917792

CC=COc1ccc(C(=O)Cl)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
HPGD P15428 6/20 0.36
MAPT P10636 3/20 0.36
RAB9A P51151 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
TCF4 P15884 1/20 0.36
CTNNB1 P35222 1/20 0.36
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
ELANE P08246 1/20 0.35
PARP1 P09874 1/20 0.34
PARP10 Q53GL7 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
PARP4 Q9UKK3 1/20 0.34
PPARA Q07869 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
HTT P42858 2/20 0.33
TSHR P16473 2/20 0.33
HIF1A Q16665 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840374 0.84 KDM4E (0.44) ALDH1A1HPGDMAPTRAB9ACES2
SCHEMBL6740579 0.82 CA1 (0.55) ALDH1A1HPGDRAB9ACA1CA2
Hydrochloric Acid SCHEMBL7917794 0.81 CA1 (0.53) ALDH1A1HPGDRAB9ACA1CA2
SCHEMBL10349941 0.79 ALDH1A1 (0.45) ALDH1A1HPGDMAPTRAB9ACES2
SCHEMBL10349942 0.79 ALDH1A1 (0.45) ALDH1A1HPGDMAPTRAB9ACES2
SCHEMBL11343755 0.79 CA1 (0.60) ALDH1A1MAPTRAB9ACA1CA2
SCHEMBL5612605 0.78 LMNA (0.39) ALDH1A1CA1CA2PPARATSHR
SCHEMBL28649673 0.78 ELANE (0.58) ALDH1A1HPGDMAPTRAB9ACES2
SCHEMBL11758434 0.76 ALDH1A1 (0.39) ALDH1A1HPGDMAPTRAB9ACES2
SCHEMBL9446383 0.76 KMT2A (0.47) ALDH1A1MAPTRAB9AELANEPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6294231-B1 Optically anisotropic film, method of manufacturing the same, and liquid crystal display apparatus SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-25 US disclosed
EP-0987310-A2 Optically anisotropic film, method of manufacturing the same, and liquid crystal display apparatus SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-22 EP disclosed
US-5695680-A Liquid crystalline doristerol-containing organosiloxanes CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1997-12-09 US disclosed
US-5682212-A DISPLAY DEVICE CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1997-10-28 US disclosed