Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840371 | 0.85 | KDM4E (0.62) | KDM4ECYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7917792 | 0.84 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL10395256 | 0.81 | GABBR2 (0.40) | KDM4ECYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3541417 | 0.78 | KDM4E (0.70) | KDM4ECYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29375279 | 0.76 | CES2 (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL727139 | 0.76 | CES2 (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL909307 | 0.75 | CA12 (0.51) | KDM4EHSD17B10MEN1KMT2ACYP3A4 | |
| SCHEMBL730510 | 0.73 | MAPT (0.46) | KDM4ECYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3306770 | 0.73 | CYP2A6 (0.54) | KDM4ECYP1A2MEN1KMT2ANPC1 | |
| SCHEMBL8775402 | 0.72 | LCK (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5695680-A | Liquid crystalline doristerol-containing organosiloxanes | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1997-12-09 | — | — | US | disclosed |