Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL195130 | 0.99 | HTT (0.41) | HTTMEN1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL7854190 | 0.76 | KMT2A (0.47) | HTTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL5733271 | 0.76 | HSD17B10 (0.64) | HTTMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL3726705 | 0.75 | LMNA (0.50) | MEN1KMT2AMAPTCYP2D6 | |
| SCHEMBL14874417 | 0.75 | CYP4F2 (0.47) | HTTMEN1KMT2AALDH1A1NR1H4 | |
| SCHEMBL3207839 | 0.75 | MEN1 (0.46) | HTTMEN1KMT2AL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6406497 | 0.74 | LMNA (0.49) | MEN1KMT2AALDH1A1MAPTCYP2D6 | |
| SCHEMBL14874302 | 0.74 | HTT (0.50) | HTTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL10961574 | 0.73 | GABRA1 (0.46) | HTTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL14874517 | 0.73 | MEN1 (0.46) | HTTMEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010098488-A1 | ARYL IMIDAZOLE COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |