Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838901 | 0.90 | HTT (0.36) | EGFRERBB2HPGDTAS1R3TAS1R1 | |
| SCHEMBL7811949 | 0.77 | TAS1R3 (0.35) | EGFRERBB2HPGDNPSR1MCOLN3 | |
| SCHEMBL22109937 | 0.75 | HPGD (0.47) | EGFRERBB2HPGDNPSR1MCOLN3 | |
| SCHEMBL6838898 | 0.71 | HTT (0.38) | HPGDTAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL246394 | 0.71 | TAS1R3 (0.41) | HPGDNPSR1MCOLN3TAS1R3TAS1R1 | |
| SCHEMBL22020474 | 0.71 | HPGD (0.44) | EGFRERBB2HPGDNPSR1MCOLN3 | |
| SCHEMBL9883885 | 0.69 | KDM4E (0.42) | HPGDTAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL25425784 | 0.69 | HPGD (0.43) | EGFRERBB2HPGDNPSR1MCOLN3 | |
| SCHEMBL4593011 | 0.69 | KDM4E (0.43) | EGFRERBB2HPGDNPSR1MCOLN3 | |
| SCHEMBL28612978 | 0.69 | TAS1R3 (0.40) | HPGDNPSR1MCOLN3TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221810-B1 | 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2001-04-24 | — | — | US | disclosed |
| US-5977029-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5780394-A | EFFECTIVE AGAINST CHEMICAL RESISTANT PESTS; PESTICIDES, HERBIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| US-5739389-A | INSECTICIDE; HERBICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| US-5661110-A | PESTICIDES; INSECTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-26 | — | — | US | disclosed |
| US-5474974-A | Insecticide, pesticide, nematocide, miticide and herbicide | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5393729-A | Pesticides, fungicides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-02-28 | — | — | US | disclosed |
| US-5358924-A | Pesticides, miticides, insecticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-25 | — | — | US | disclosed |
| US-5332720-A | 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | disclosed |