Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918128 | 0.90 | EGFR (0.36) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL6838898 | 0.80 | HTT (0.38) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL18033973 | 0.75 | HTT (0.44) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL7479979 | 0.74 | HTT (0.34) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL7811949 | 0.72 | TAS1R3 (0.35) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL9737304 | 0.71 | ALDH1A1 (0.52) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL4639714 | 0.70 | POLB (0.53) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL7270831 | 0.68 | ALDH1A1 (0.52) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL22754120 | 0.67 | CYP3A4 (0.50) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL6308979 | 0.67 | KMT2A (0.38) | HTTTSHRALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759548-B2 | PESTICIDES AND HERBICIDES. PHENYL-SUBSTITUTED CYCLIC KETOENOLS, A PLURALITY OF PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-06 | — | — | US | disclosed |
| US-20030144504-A1 | Pesticides and herbicides. phenyl-substituted cyclic ketoenols, a plurality of processes and intermediates for their preparation | FISCHER REINER (DE) | 2003-07-31 | — | — | US | disclosed |
| US-6469196-B2 | PESTICIDES AND WEEDKILLERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| US-20020022575-A1 | Dialkyl-halogenophenyl-substituted ketoenols | FISCHER REINER (DE) | 2002-02-21 | — | — | US | disclosed |
| US-6251830-B1 | PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| US-5994274-A | Dialkyl phenyl halide-substituted keto-enols for use as herbicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144504-A1 | Pesticides and herbicides. phenyl-substituted cyclic ketoenols, a plurality of processes and intermediates for their preparation | DDT, CYP8B1, CYP1A1 | HTT 852/4885TSHR 1710/4885ALDH1A1 566/4885 |
| US-20020022575-A1 | Dialkyl-halogenophenyl-substituted ketoenols | DDT, CYP2E1, CYP8B1 | HTT 1731/4885TSHR 1183/4885ALDH1A1 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.