Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908683 | 0.89 | BRS3 (0.36) | FNTAFNTB | |
| SCHEMBL7908805 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRPDE4DPDE7AKMT2A | |
| SCHEMBL7918313 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRPDE4DPDE7AKMT2A | |
| SCHEMBL7908657 | 0.79 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL7921829 | 0.79 | FNTA (0.39) | ALDH1A1TSHRPDE4DPDE7AKMT2A | |
| SCHEMBL7916606 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRPDE4DPDE7AKMT2A | |
| SCHEMBL7869014 | 0.74 | FNTA (0.42) | ALDH1A1TSHRPDE4DPDE7AKMT2A | |
| Decarboxylated Derivative SCHEMBL628807 | 0.73 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL628805 | 0.73 | BACE1 (0.40) | ALDH1A1TSHR | |
| Decarboxylated Derivative SCHEMBL629210 | 0.73 | FNTA (0.41) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |