Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918595 | 0.90 | FNTA (0.40) | FNTAFNTB | |
| SCHEMBL7917806 | 0.89 | CNR1 (0.41) | CNR2CNR1ALDH1A1KMT2A | |
| SCHEMBL7916606 | 0.88 | ALDH1A1 (0.37) | FNTAFNTBALDH1A1TSHRPDE4D | |
| SCHEMBL7908805 | 0.84 | ALDH1A1 (0.36) | FNTAFNTBALDH1A1TSHRPDE4D | |
| SCHEMBL7918851 | 0.82 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL7918697 | 0.82 | BRS3 (0.37) | FNTAFNTB | |
| SCHEMBL7918230 | 0.80 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL7918323 | 0.79 | ALDH1A1 (0.36) | FNTAFNTBALDH1A1TSHRPDE4D | |
| SCHEMBL7918313 | 0.78 | ALDH1A1 (0.36) | FNTAFNTBALDH1A1TSHRPDE4D | |
| SCHEMBL7915090 | 0.77 | MYC (0.39) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |