Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918601 | 0.90 | FNTA (0.38) | FNTAFNTB | |
| SCHEMBL7918232 | 0.82 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL629649 | 0.81 | FNTA (0.37) | FNTAFNTB | |
| SCHEMBL7908810 | 0.81 | FNTA (0.39) | FNTAFNTB | |
| SCHEMBL7874202 | 0.77 | GCK (0.36) | GCK | |
| SCHEMBL628805 | 0.77 | BACE1 (0.40) | — | |
| SCHEMBL7870248 | 0.76 | METAP2 (0.45) | — | |
| Hydrochloric Acid SCHEMBL629208 | 0.76 | BACE1 (0.40) | — | |
| SCHEMBL629753 | 0.75 | FNTA (0.43) | FNTAFNTB | |
| Decarboxylated Derivative SCHEMBL628807 | 0.71 | FNTA (0.41) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |