Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915297 | 0.83 | KMT2A (0.47) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL4623724 | 0.81 | ALDH1A1 (0.57) | MAPTKMT2AMEN1NPC1LMNA | |
| SCHEMBL7908561 | 0.78 | NPC1 (0.54) | MAPTGAAKMT2AMEN1NPC1 | |
| SCHEMBL7918203 | 0.77 | SMN1; SMN2 (0.41) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3090261 | 0.76 | KMT2A (0.56) | MAPTGAAKMT2AMEN1RAB9A | |
| SCHEMBL11858419 | 0.74 | ALDH1A1 (0.53) | MAPTKMT2AMEN1NPC1LMNA | |
| SCHEMBL11643606 | 0.72 | KMT2A (0.59) | MAPTGAAKMT2AMEN1RAB9A | |
| SCHEMBL10305757 | 0.72 | SIRT2 (0.47) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL358841 | 0.71 | NPC1 (0.48) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9163164 | 0.70 | MAPT (0.48) | MAPTGAAKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200831-B1 | HEAT-CURING A COATING OF A POLYAMIC ACID BASED ON A TETRACARBOXYLIC ACID AND A DIAMINE CONTAINNG AN ACTIVE OXYGEN OR NITROGEN FUNCTIONAL GROUP; SEALING THE EXTERNAL TERMINALS WITH A RESIN, E.G. AN EPOXIDE | HITACHI, LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| US-6087006-A | SEMICONDUCTOR DEVICE HAVING SURFACE-PROTECTING FILM COMPRISING POLYIMIDE OBTAINED BY HEAT-CURING PRECURSOR HAVING POLAR SUBSTITUENTS AS THE SIDE CHAINS | HITACHI, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |