SCHEMBL7918989

SCHEMBL7918989

O=CC1=CC(Cl)c2ccccc2C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 3/20 0.41
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
MAPK1 P28482 3/20 0.34
CYP1A2 P05177 3/20 0.34
KMT2A Q03164 5/20 0.33
MEN1 O00255 4/20 0.33
IDO1 P14902 1/20 0.33
DNMT1 P26358 1/20 0.33
DNMT3L Q9UJW3 1/20 0.33
DNMT3A Q9Y6K1 1/20 0.33
CDC25B P30305 1/20 0.33
POLB P06746 2/20 0.32
LMNA P02545 3/20 0.32
THRB P10828 2/20 0.32
BLM P54132 2/20 0.32
RAB9A P51151 2/20 0.32
MAPT P10636 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7745983 0.70 EDNRB (0.46) S100A4EDNRBEDNRAMAPK1CYP1A2
SCHEMBL7912897 0.69 EDNRB (0.41) S100A4EDNRBEDNRACYP1A2KMT2A
SCHEMBL6904734 0.68 MEN1 (0.52) S100A4EDNRBEDNRAMAPK1CYP1A2
SCHEMBL29006544 0.65 S100A4 (0.50) S100A4EDNRBEDNRAMAPK1CYP1A2
SCHEMBL27952806 0.65 KMT2A (0.36) S100A4EDNRBEDNRAMAPK1CYP1A2
SCHEMBL17219870 0.63 APEX1 (0.54) S100A4MAPK1CYP1A2KMT2AMEN1
SCHEMBL31665886 0.63 APEX1 (0.54) S100A4MAPK1CYP1A2KMT2AMEN1
SCHEMBL30139895 0.63 CDC25B (0.46) S100A4MAPK1CYP1A2KMT2AMEN1
SCHEMBL6903914 0.62 MAPK1 (0.67) S100A4EDNRBEDNRAMAPK1CYP1A2
SCHEMBL16047150 0.62 IDO1 (0.46) S100A4EDNRBEDNRAMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed