SCHEMBL7912897

SCHEMBL7912897

CC(=O)C1=CC(Cl)c2ccccc2C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.41
EDNRA P25101 1/20 0.41
STAT3 P40763 2/20 0.40
NFKB1 P19838 1/20 0.40
STAT1 P42224 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
KMT2A Q03164 1/20 0.39
POLB P06746 2/20 0.39
PTPN6 P29350 1/20 0.37
S100A4 P26447 2/20 0.37
HSP90AA1 P07900 2/20 0.36
HSP90AB1 P08238 2/20 0.36
APEX1 P27695 2/20 0.36
ALDH1A1 P00352 3/20 0.35
HPGD P15428 1/20 0.35
CYP1A2 P05177 1/20 0.35
TSHR P16473 1/20 0.35
APAF1 O14727 1/20 0.34
TDP2 O95551 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7745983 0.85 EDNRB (0.46) EDNRBEDNRAKMT2AS100A4ALDH1A1
SCHEMBL7918989 0.69 S100A4 (0.41) EDNRBEDNRAKMT2APOLBS100A4
SCHEMBL27952806 0.66 KMT2A (0.36) EDNRBEDNRAKMT2APOLBS100A4
SCHEMBL49598 0.66 CDC25A (0.53) NFKB1NFKB2RELAKMT2APTPN6
SCHEMBL30645249 0.66 CDC25B (0.47) STAT3NFKB1STAT1NFKB2RELA
SCHEMBL6904734 0.65 MEN1 (0.52) EDNRBEDNRAKMT2APOLBS100A4
SCHEMBL6904886 0.63 POLB (0.59) EDNRBEDNRAKMT2APOLBALDH1A1
SCHEMBL29006544 0.62 S100A4 (0.50) EDNRBEDNRAKMT2APOLBS100A4
SCHEMBL25003447 0.62 POLB (0.41) KMT2APOLBALDH1A1CYP1A2MAPT
SCHEMBL2320565 0.62 ALDH1A1 (0.47) STAT3KMT2AS100A4HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed