Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807993 | 0.82 | GAA (0.45) | MCL1GAAHPGDLMNANPC1 | |
| SCHEMBL4793277 | 0.81 | GAA (0.50) | MCL1GAAHPGDLMNAOPRM1 | |
| SCHEMBL7919195 | 0.80 | MCL1 (0.40) | MCL1POLBCTSLCTSSLMNA | |
| SCHEMBL7909507 | 0.80 | MCL1 (0.49) | MCL1GAAHPGDPOLBCTSL | |
| SCHEMBL8175414 | 0.78 | POLB (0.50) | GAAPOLBLMNANPC1RAB9A | |
| SCHEMBL7421662 | 0.78 | ALDH1A1 (0.51) | GAAPOLBLMNANPC1RAB9A | |
| SCHEMBL8366340 | 0.77 | TP53 (0.50) | GAAHPGDLMNAOPRM1OPRL1 | |
| SCHEMBL6184360 | 0.76 | CTSS (0.56) | MCL1POLBCTSLCTSSLMNA | |
| SCHEMBL654148 | 0.75 | MCL1 (1.00) | MCL1GAAHPGDLMNARAB9A | |
| SCHEMBL8749389 | 0.75 | POLB (0.51) | MCL1POLBCTSLCTSSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211270-B1 | HEAT AND LIGHT STABILIZERS FOR POLYMERS | WITCO VINYL ADDITIVES GMBH (DE) | 2001-04-03 | — | — | US | disclosed |