SCHEMBL7919262

SCHEMBL7919262

C=[Ti](OC(=O)c1cccc2ccccc12)(OC(=O)c1cccc2ccccc12)(C1=CC=CC1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.34
HTR2B P41595 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
HRH3 Q9Y5N1 1/20 0.33
KMT2A Q03164 4/20 0.32
MEN1 O00255 3/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP2C9 P11712 3/20 0.32
LMNA P02545 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
CYP2C19 P33261 1/20 0.32
KCNH2 Q12809 1/20 0.32
GAA P10253 2/20 0.32
POLB P06746 2/20 0.32
CXCR5 P32302 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930315 0.89 HTR7 (0.40) HTR7HTR2BNPC1RAB9AHRH3
SCHEMBL7923902 0.85 NPC1 (0.37) HTR7HTR2BNPC1RAB9AKMT2A
SCHEMBL7927106 0.84 NPC1 (0.41) HTR7HTR2BNPC1RAB9AKMT2A
SCHEMBL7927145 0.83 KMT2A (0.42) NPC1RAB9AHRH3KMT2AMEN1
SCHEMBL7919196 0.82 NPC1 (0.36) HTR7HTR2BNPC1RAB9AKMT2A
SCHEMBL7928345 0.82 NPC1 (0.38) HTR7HTR2BNPC1RAB9A
SCHEMBL7930755 0.82 MAPT (0.35) HTR7HTR2BNPC1RAB9AKMT2A
SCHEMBL7927137 0.81 NPC1 (0.39) HTR7HTR2BNPC1RAB9ACYP1A2
SCHEMBL7919135 0.81 NPC1 (0.39) HTR7HTR2BNPC1RAB9AMAPT
SCHEMBL7925868 0.81 NPC1 (0.37) HTR7HTR2BNPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed