Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10398568 | 0.85 | CRHBP (0.65) | CRHBPCRHR2ALDH1A1GAACYP3A4 | |
| SCHEMBL6560324 | 0.82 | ALDH1A1 (0.46) | CRHBPCRHR2ALDH1A1CYP3A4CASP1 | |
| SCHEMBL2020210 | 0.82 | SIGMAR1 (0.47) | ALDH1A1CYP3A4CASP1RECQLPBRM1 | |
| SCHEMBL10946709 | 0.82 | ALDH1A1 (0.42) | CRHBPCRHR2ALDH1A1CYP3A4CASP1 | |
| SCHEMBL15640887 | 0.78 | SIGMAR1 (0.47) | CRHBPCRHR2ALDH1A1CYP3A4CASP1 | |
| SCHEMBL27784974 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CASP1RECQLPBRM1 | |
| SCHEMBL9514177 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP3A4PBRM1DDX3XTSHR | |
| SCHEMBL8374423 | 0.78 | ALDH1A1 (0.57) | CRHBPCRHR2ALDH1A1GAACYP3A4 | |
| SCHEMBL9998812 | 0.78 | CRHBP (0.53) | CRHBPCRHR2ALDH1A1GAALMNA | |
| SCHEMBL9834822 | 0.77 | PARP1 (0.53) | CRHBPCRHR2GAACYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160179-A | Method of producing 4-nitro-m-phenylenediamine sulfate | GIANNOTTI JAMES (US) | 2000-12-12 | — | — | US | claimed |
| CN-116284641-A | Surface chemical modification method of aromatic primary diamine particles for polyurethane elastomer material and application thereof | 苏州湘园新材料股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-6228547-B1 | CHARGE TRANSFER COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-05-08 | — | — | US | disclosed |
| EP-0159291-A1 | Ink composition for the ink-jet printing process | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4062838-A | LACQUERS, PRINTING INKS, YELLOW TO ORANGE | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |