SCHEMBL791984

SCHEMBL791984

COC[C@H](N)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 10/20 0.61
TACR1 P25103 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57799 1.00 SCN4A (0.61) SCN4ATACR1
SCHEMBL1419721 1.00 SCN4A (0.61) SCN4ATACR1
Hydrochloric Acid SCHEMBL22229209 0.98 SCN4A (0.59) SCN4ATACR1
Hydrochloric Acid SCHEMBL7757109 0.98 SCN4A (0.59) SCN4ATACR1
Hydrochloric Acid SCHEMBL56787 0.98 SCN4A (0.59) SCN4ATACR1
SCHEMBL12789473 0.88 SCN4A (0.53) SCN4ATACR1
SCHEMBL90024 0.84 SCN4A (0.48) SCN4ATACR1
SCHEMBL19312226 0.84 SCN4A (0.48) SCN4ATACR1
SCHEMBL90002 0.84 SCN4A (0.48) SCN4ATACR1
SCHEMBL2782707 0.83 SCN4A (0.68) SCN4ATACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8378117-B2 1-(4-fluoro-phenyl)-8-(4-methyl-benzyl)-1,4,5,6,7,8-hexahydro-cycloheptapyrazole-3-carboxylic acid (1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amide; antidepressant, anxiolytic; nervous system disorders, metabolic disorders, obesity JANSSEN PHARMACEUTICA N.V. (BE) 2013-02-19 US claimed
US-7825151-B2 Hexahydro-cyclooctyl pyrazole cannabinoid modulators JANSSEN PHARMACEUTICA NV (BE) 2010-11-02 US claimed
US-20090215850-A1 METHOD FOR TREATING CB2 RECEPTOR MEDIATED PAIN JANSSEN PHARMACEUTICA N.V. (BE) 2009-08-27 US claimed
US-20080234347-A1 METHOD FOR TREATING CB2 RECEPTOR MEDIATED PAIN JANSSEN PHARMACEUTICA N.V. (BE) 2008-09-25 US claimed
US-20080076814-A1 Hexahydro-Cyclooctyl Pyrazole Cannabinoid Modulators JANSSEN PHARMACEUTICA N.V. (BE) 2008-03-27 US claimed
US-20080070968-A1 Hexahydro-Cycloheptapyrazole Cannabinoid Modulators JANSSEN PHARMACEUTICA N.V. (BE) 2008-03-20 US claimed
EP-0776883-A1 Adduct salts of substituted benzylamine and a process for optically resolving them Ajinomoto Co., Inc. (JP) 1997-06-04 EP claimed
US-20260103455-A1 ULK3 INHIBITORS AND USES THEREOF H LEE MOFFITT CANCER CT & RES (US) 2026-04-16 US disclosed
EP-4680265-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC AND LIVER DISORDERS Viking Therapeutics, Inc. (US) 2026-01-21 EP disclosed
US-20250340539-A1 IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1, AND/OR CLK4 PERHA PHARMACEUTICALS (FR) 2025-11-06 US disclosed
US-20250340538-A1 IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 PERHA PHARMACEUTICALS (FR) 2025-11-06 US disclosed
EP-4143185-B1 NEW IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 PERHA PHARMACEUTICALS (FR) 2025-10-29 EP disclosed
EP-4638446-A1 THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF Ventus Therapeutics U.S., Inc. (US) 2025-10-29 EP disclosed
EP-0776883-A1 Adduct salts of substituted benzylamine and a process for optically resolving them Ajinomoto Co., Inc. (JP) 1997-06-04 EP disclosed
EP-0750622-A1 ALPHA-AMINOPHOSPHONATES AND PROCESSES FOR THEIR PREPARATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1997-01-02 EP disclosed
EP-0719789-A1 Process of producing alpha-L-aspartyldipeptide amide derivatives Ajinomoto Co., Ltd. (JP) 1996-07-03 EP disclosed
US-5508463-A ENANTIOMERICALLY PURE INTERMEDIATES TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1996-04-16 US disclosed
WO-1996004274-A1 AZETIDINE, PYRROLIDINE AND PIPERIDINE DERIVATIVES MERCK SHARP & DOHME LIMITED (GB) 1996-02-15 WO disclosed
EP-0691346-A1 Novel aspartyldipeptide derivatives and sweetener Ajinomoto Co., Inc. (JP) 1996-01-10 EP disclosed
WO-1995025111-A1 α-AMINOPHOSPHONATES AND PROCESSES FOR THEIR PREPARATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1995-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215850-A1 METHOD FOR TREATING CB2 RECEPTOR MEDIATED PAIN CNR2, CNR1, NPY4R SCN4A 413/4885TACR1 116/4885
US-20080070968-A1 Hexahydro-Cycloheptapyrazole Cannabinoid Modulators CNR2, CNR1, FAAH SCN4A 1191/4885TACR1 127/4885
US-20250340538-A1 IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 CLK1, CLK2, CLK3 SCN4A 4079/4885TACR1 3318/4885
US-20080234347-A1 METHOD FOR TREATING CB2 RECEPTOR MEDIATED PAIN CNR2, CNR1, NPY4R SCN4A 413/4885TACR1 116/4885
US-20080076814-A1 Hexahydro-Cyclooctyl Pyrazole Cannabinoid Modulators CNR1, CNR2, FAAH SCN4A 1439/4885TACR1 223/4885
US-20260103455-A1 ULK3 INHIBITORS AND USES THEREOF ULK3, ULK1, ULK2 SCN4A 3906/4885TACR1 4764/4885
US-20250340539-A1 IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1, AND/OR CLK4 CLK1, CLK2, CLK3 SCN4A 4378/4885TACR1 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.