Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23819974 | 0.84 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL28755243 | 0.84 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL1710167 | 0.84 | LMNA (0.59) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL12633216 | 0.84 | LMNA (0.59) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL1870853 | 0.84 | LMNA (0.59) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL31529358 | 0.83 | CA1 (0.45) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL25980431 | 0.83 | CA1 (0.45) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL11410151 | 0.80 | MAPT (0.51) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL11410152 | 0.80 | MAPT (0.51) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL10714107 | 0.77 | HPGD (0.53) | ALDH1A1LMNAKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225499-B1 | REACTING N-ARYLMETHYLIDENE AMINOARYLBROMIDE WITH TERMINAL ACETYLENE IN PRESENCE OF BASE AND CATALYST SYSTEM COMPRISING PALLADIUM CATALYST AND CUPROUS SALT TO PRODUCE N-ARYLMETHYLIDENE AMINOARYLACETYLENE | CATALYTICA PHARMACEUTICALS, INC. | 2001-05-01 | — | — | US | claimed |
| CN-108276294-A | A kind of preparation method of fluorine-containing benzidine | 上海康鹏科技有限公司 | 2018-07-13 | — | — | CN | disclosed |