Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12633216 | 1.00 | LMNA (0.59) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1870853 | 1.00 | LMNA (0.59) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL10714107 | 0.87 | HPGD (0.53) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL14524455 | 0.86 | LMNA (0.55) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5078683 | 0.86 | LMNA (0.55) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5078680 | 0.86 | LMNA (0.55) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL12633222 | 0.84 | DHODH (0.51) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3727579 | 0.84 | MAPT (0.50) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7636431 | 0.84 | CYP2C9 (0.52) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1867533 | 0.84 | DHODH (0.51) | LMNAKDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217006-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| EP-2344511-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2011-07-20 | — | — | EP | disclosed |
| US-20110108822-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |
| WO-2010054728-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110108822-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | ICMT, ORAI2, EPCAM | LMNA 2068/4885KDM4E 3623/4885ALDH1A1 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.