Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.51 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024613 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HSD17B10ADORA3MAPTTSHR | |
| SCHEMBL8562068 | 0.83 | HPGD (0.66) | ALDH1A1HSD17B10POLBCACNA1FCACNA1D | |
| SCHEMBL8394358 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HSD17B10POLBMAPTTSHR | |
| SCHEMBL15322914 | 0.80 | MAPT (0.46) | ALDH1A1HSD17B10ADORA3POLBCACNA1D | |
| SCHEMBL3905675 | 0.79 | ADORA3 (0.83) | ALDH1A1HSD17B10ADORA3POLBCACNA1F | |
| SCHEMBL5363492 | 0.78 | TSHR (0.74) | ALDH1A1HSD17B10ADORA3POLBTSHR | |
| SCHEMBL14407560 | 0.77 | ALDH1A1 (0.61) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL8561209 | 0.76 | ABCC1 (0.63) | ALDH1A1HSD17B10ADORA3POLBCACNA1F | |
| SCHEMBL9088494 | 0.76 | ADORA3 (0.76) | ALDH1A1HSD17B10ADORA3POLBCACNA1F | |
| SCHEMBL6951320 | 0.76 | ADORA3 (0.76) | ALDH1A1HSD17B10ADORA3POLBCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221550-B1 | IMPROVES THE CHARGING CHARACTERISTICS OF A TONER, SO THAT THE TONER QUICKLY CHARGES TO A NEGATIVE VALUE THAT IS THEN SUBSTANTIALLY MAINTAINED | NEXPRESS SOLUTIONS LLC | 2001-04-24 | — | — | US | disclosed |