Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.56 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.56 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562068 | 0.92 | HPGD (0.66) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL8024613 | 0.80 | ALDH1A1 (0.67) | HPGDSMN1; SMN2KDM4EADORA3ACHE | |
| SCHEMBL3030945 | 0.77 | ABCC1 (1.00) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL7920096 | 0.76 | ALDH1A1 (0.66) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL8562368 | 0.75 | HPGD (0.46) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL8040446 | 0.75 | KDM4E (0.46) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL8381158 | 0.74 | ALDH1A1 (0.78) | HPGDSMN1; SMN2KDM4EHTTKMT2A | |
| SCHEMBL10895180 | 0.74 | CACNA1F (0.76) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL8558368 | 0.74 | KDM4E (0.47) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL10886798 | 0.73 | ADORA3 (0.72) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760073-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |