Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038214 | 0.86 | MAPT (0.33) | MEN1USP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7920156 | 0.79 | MEN1 (0.43) | MEN1USP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7928543 | 0.75 | DHODH (0.38) | MEN1USP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5722885 | 0.72 | MEN1 (0.43) | MEN1USP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8038196 | 0.72 | RARB (0.47) | MEN1USP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL14062487 | 0.72 | RAB9A (0.55) | MEN1USP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5722659 | 0.70 | LPL (0.36) | TLR8RARB | |
| SCHEMBL9330847 | 0.69 | RARB (0.54) | MEN1USP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9331013 | 0.69 | RARB (0.54) | MEN1USP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7558492 | 0.69 | MAPK1 (0.43) | MEN1USP2ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946474-B1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-07 | — | — | EP | disclosed |
| US-6159561-A | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |