Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925295 | 0.87 | CYP1A2 (0.41) | ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL3758134 | 0.81 | CHUK (0.44) | ALDH1A1SLC6A3LMNAMAPT | |
| SCHEMBL29607397 | 0.81 | CHUK (0.44) | ALDH1A1SLC6A3LMNAMAPT | |
| SCHEMBL28748440 | 0.81 | CHUK (0.44) | ALDH1A1SLC6A3LMNAMAPT | |
| SCHEMBL7920894 | 0.80 | PDE4B (0.40) | PDE4APDE4DPDE4BPDE4CPPARG | |
| SCHEMBL7920527 | 0.80 | PPARG (0.37) | PDE4APDE4DPDE4BPDE4CNPC1 | |
| SCHEMBL7922511 | 0.80 | SMPD1 (0.45) | PDE4APDE4DPDE4BPDE4CPDE3B | |
| SCHEMBL7931605 | 0.78 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7929583 | 0.76 | FDPS (0.52) | PDE4APDE4DPDE4BPDE4CNPC1 | |
| SCHEMBL29101743 | 0.76 | SMPD1 (0.50) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |