Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848842 | 0.81 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1ACHETSHR | |
| SCHEMBL278364 | 0.80 | TSHR (0.41) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL14733092 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL8400164 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL23145454 | 0.79 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL8849127 | 0.78 | DGKA (0.38) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL11528628 | 0.77 | LMNA (0.37) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL5576745 | 0.77 | LMNA (0.37) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL10633499 | 0.77 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL1434500 | 0.77 | LMNA (0.46) | ALDH1A1LMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931768-B1 | NITROFUNCTIONAL ACRYLATE COPOLYMERS FOR BINDER COMPOSITIONS | ANGUS CHEMICAL (US) | 2017-08-16 | — | — | EP | disclosed |
| US-6194461-B1 | USEFUL AS MEDICAMENT FOR TREATING RETINAL DEGENERATIVE DISORDERS; ALPHA-(2,4-DIFLUOROPHENYL)-N-T-BUTYLNITRONE, AND CORRESPONDING AMINES WHICH WOULD BE CONVERTED IN VIVO TO THE NITRONE, FOR EXAMPLE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| CN-1238759-A | Nitrone derivatives | SUMITOMO PHARMA (JP) | 1999-12-15 | — | — | CN | disclosed |
| EP-0945426-A1 | NITRONE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-09-29 | — | — | EP | disclosed |