Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 2/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 2/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 1.00 |
| ▸ | USP7 | Q93009 | 2/20 | 1.00 |
| ▸ | PYGM | P11217 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.80 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.80 |
| ▸ | GABRP | O00591 | 1/20 | 0.80 |
| ▸ | GABRD | O14764 | 1/20 | 0.80 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.80 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.80 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.80 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.80 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.80 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.80 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Corosolic Acid SCHEMBL3290746 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL1280250 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL13735311 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL4456541 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL12181612 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL4962208 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL12740947 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL13629638 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL22027588 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 | |
| Corosolic Acid SCHEMBL4456542 | 1.00 | HSD11B1 (1.00) | HSD11B1POLBPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001504514-A | — | — | 2001-04-03 | — | — | JP | claimed |
| EP-0959890-A1 | MEDICINES FOR TREATING DEMENTIA OR COGNITIVE DISORDER, WHICH COMPRISES ASIATIC ACID DERIVATIVES | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1999-12-01 | — | — | EP | claimed |
| WO-1998023278-A1 | MEDICINES FOR TREATING DEMENTIA OR COGNITIVE DISORDER, WHICH COMPRISES ASIATIC ACID DERIVATIVES | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1998-06-04 | — | — | WO | claimed |
| EP-3340992-B1 | METHOD FOR TREATMENT OF MONOCYTE DYSFUNCTION AND CHRONIC INFLAMMATORY MICRO-AND MACRO-VASCULAR DISEASES | UNIV TEXAS (US) | 2022-12-28 | — | — | EP | disclosed |
| US-20180250309-A1 | METHODS FOR TREATMENT OF MONOCYTE DYSFUNCTION AND CHRONIC INFLAMMATORY MICRO AND MACRO-VASCULAR DISEASES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-09-06 | — | — | US | disclosed |
| EP-3340992-A1 | METHOD FOR TREATMENT OF MONOCYTE DYSFUNCTION AND CHRONIC INFLAMMATORY MICRO-AND MACRO-VASCULAR DISEASES | Asmis, Reto (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017041077-A1 | METHOD FOR TREATMENT OF MONOCYTE DYSFUNCTION AND CHRONIC INFLAMMATORY MICRO-AND MACRO-VASCULAR DISEASES | ASMIS RETO (US) | 2017-03-09 | — | — | WO | disclosed |
| EP-0959890-A1 | MEDICINES FOR TREATING DEMENTIA OR COGNITIVE DISORDER, WHICH COMPRISES ASIATIC ACID DERIVATIVES | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1999-12-01 | — | — | EP | disclosed |
| US-5834437-A | WOUND HEALING AGENTS | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1998-11-10 | — | — | US | disclosed |
| WO-1998023278-A1 | MEDICINES FOR TREATING DEMENTIA OR COGNITIVE DISORDER, WHICH COMPRISES ASIATIC ACID DERIVATIVES | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1998-06-04 | — | — | WO | disclosed |
| WO-1996017819-A1 | ASIATIC ACID DERIVATIVES, ITS MANUFACTURING METHOD AND DERMATOLOGICAL AGENT CONTAINING IT | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1996-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180250309-A1 | METHODS FOR TREATMENT OF MONOCYTE DYSFUNCTION AND CHRONIC INFLAMMATORY MICRO AND MACRO-VASCULAR DISEASES | CD14, CD68, MYD88 | HSD11B1 217/4885POLB 3122/4885PTPN2 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.