SCHEMBL7921355

SCHEMBL7921355

O=C1N(c2ccccc2)C(=O)C12CC1C=CC2C1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.40
POLB P06746 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
FPR1 P21462 1/20 0.36
MGLL Q99685 1/20 0.35
ATM Q13315 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17479537 1.00 ELANE (0.40) ELANEPOLBMEN1KMT2AALDH1A1
SCHEMBL13025196 0.77 ALDH1A1 (0.35) ELANEPOLBMEN1KMT2AALDH1A1
SCHEMBL16034793 0.75
SCHEMBL5322625 0.75 ALDH1A1 (0.33) ALDH1A1
SCHEMBL9705137 0.75 CYP2D6 (0.37)
SCHEMBL11740261 0.74 MAOB (0.36)
SCHEMBL18107021 0.69 CYP2D6 (0.33)
SCHEMBL17503523 0.69 CYP2D6 (0.36)
SCHEMBL6254118 0.67 CYP2D6 (0.35)
SCHEMBL1739099 0.67 KDM1A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1029420-A None JP disclosed
EP-3080170-B1 INSERTION POLYNORBORNENE-BASED THERMOSET RESINS TRANSFERT PLUS SEC (CA) 2020-02-05 EP disclosed
US-20160311970-A1 INSERTION POLYNORBORNENE-BASED THERMOSET RESINS CLAVERIE, Jérôme (CA) 2016-10-27 US disclosed
EP-3080170-A1 INSERTION POLYNORBORNENE-BASED THERMOSET RESINS Transfert Plus, S.E.C. (CA) 2016-10-19 EP disclosed
WO-2015085428-A1 INSERTION POLYNORBORNENE-BASED THERMOSET RESINS TRANSFERT PLUS, SOCIÉTÉ EN COMMANDITE (CA) 2015-06-18 WO disclosed
EP-0828768-B1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION GOODRICH CO B F (US) 2001-04-18 EP disclosed
EP-0828764-B1 ADDITION POLYMERS OF POLYCYCLOOLEFINS CONTAINING FUNCTIONAL SUBSTITUENTS GOODRICH CO B F (US) 2000-09-06 EP disclosed
EP-0828768-A1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION The B.F. Goodrich Company (US) 1998-03-18 EP disclosed
EP-0828764-A1 ADDITION POLYMERS OF POLYCYCLOOLEFINS CONTAINING FUNCTIONAL SUBSTITUENTS The B.F. Goodrich Company (US) 1998-03-18 EP disclosed
US-5705503-A Addition polymers of polycycloolefins containing functional substituents SUMITOMO BAKELITE CO., LTD. (JP) 1998-01-06 US disclosed
US-5677405-A COPOLYMER OF NORBORNENE-TYPE MONOMER WHICH UNDERGOES ADDITION POLYMERIZATION AND CATIONICALLY POLYMERIZABLE MONOMER THE B.F. GOODRICH COMPANY (US) 1997-10-14 US disclosed
WO-1996037529-A1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION THE B.F. GOODRICH COMPANY (US) 1996-11-28 WO disclosed
WO-1996037526-A1 ADDITION POLYMERS OF POLYCYCLOOLEFINS CONTAINING FUNCTIONAL SUBSTITUENTS THE B.F. GOODRICH COMPANY (US) 1996-11-28 WO disclosed