Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921355 | 1.00 | ELANE (0.40) | ELANEPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL13025196 | 0.77 | ALDH1A1 (0.35) | ELANEPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL16034793 | 0.75 | — | — | |
| SCHEMBL5322625 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9705137 | 0.75 | CYP2D6 (0.37) | — | |
| SCHEMBL11740261 | 0.74 | MAOB (0.36) | — | |
| SCHEMBL18107021 | 0.69 | CYP2D6 (0.33) | — | |
| SCHEMBL17503523 | 0.69 | CYP2D6 (0.36) | — | |
| SCHEMBL6254118 | 0.67 | CYP2D6 (0.35) | — | |
| SCHEMBL1739099 | 0.67 | KDM1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210301078-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-30 | — | — | US | disclosed |
| US-11072681-B2 | Compositions and methods of making polymerizing nucleic acids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-27 | — | — | US | disclosed |
| US-20170327633-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-11-16 | — | — | US | disclosed |
| WO-2016018917-A2 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZED NUCLEIC ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORIA (US) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11072681-B2 | Compositions and methods of making polymerizing nucleic acids | RNGTT, NSUN2, POLN | ELANE 2296/4885POLB 9/4885MEN1 1524/4885 |
| US-20170327633-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | RNGTT, NSUN2, POLN | ELANE 2296/4885POLB 9/4885MEN1 1524/4885 |
| US-20210301078-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | RNGTT, NSUN2, POLN | ELANE 2296/4885POLB 9/4885MEN1 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.