Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.36 |
| ▸ | MAOA | P21397 | 8/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | SCN11A | Q9UI33 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651196 | 0.81 | ESR2 (0.35) | ALOX5AP | |
| SCHEMBL1732423 | 0.77 | MAOB (0.34) | MAOBMAOAKDM1AGRIN2DGRIN3B | |
| SCHEMBL1732130 | 0.77 | MAOB (0.52) | MAOBMAOAKDM1A | |
| SCHEMBL6528313 | 0.77 | MAOA (0.41) | MAOBMAOAKDM1A | |
| SCHEMBL1733750 | 0.77 | MAOB (0.34) | MAOBMAOAKDM1AGRIN2DGRIN3B | |
| SCHEMBL231895 | 0.77 | MAOA (0.41) | MAOBMAOAKDM1A | |
| SCHEMBL745582 | 0.77 | PTGS2 (0.44) | MAOBMAOAOPRM1OPRL1 | |
| SCHEMBL17479537 | 0.74 | ELANE (0.40) | — | |
| SCHEMBL7921355 | 0.74 | ELANE (0.40) | — | |
| SCHEMBL1733139 | 0.73 | CYP2D6 (0.41) | MAOBMAOAKDM1AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033982-A | REACTING NORBORNENES WITH SULFUR | GENERAL ELECTRIC COMPANY (US) | 1977-07-05 | — | — | US | disclosed |