Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.54 |
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | DRD3 | P35462 | 6/20 | 0.54 |
| ▸ | HRH2 | P25021 | 4/20 | 0.54 |
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915448 | 0.90 | KDM4E (0.46) | DRD4DRD2DRD3HRH2HRH1 | |
| SCHEMBL7924162 | 0.90 | KDM4E (0.62) | DRD4DRD2DRD3HRH2HRH1 | |
| SCHEMBL6139831 | 0.88 | LMNA (0.56) | DRD4DRD2DRD3LMNAMAPT | |
| SCHEMBL7927130 | 0.88 | MEN1 (0.54) | DRD4DRD2DRD3KDM4ELMNA | |
| SCHEMBL7927375 | 0.87 | KDM4E (0.54) | DRD4DRD2DRD3HRH2HRH1 | |
| SCHEMBL7921974 | 0.87 | CA12 (0.56) | LMNAMAPTHSD17B10TDP1TSHR | |
| SCHEMBL7923134 | 0.86 | KDM4E (0.53) | DRD4DRD2DRD3HRH2HRH1 | |
| SCHEMBL7921965 | 0.86 | ABCB1 (0.43) | DRD4DRD2LMNAMAPTTSHR | |
| SCHEMBL7915276 | 0.86 | LMNA (0.53) | KDM4ELMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL7924072 | 0.85 | LMNA (0.50) | DRD4LMNAHTTMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |