Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12230553 | 0.91 | HPGD (0.39) | F2RHPGDMEN1KMT2ANPSR1 | |
| SCHEMBL7911135 | 0.89 | ALDH1A1 (0.34) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7922030 | 0.88 | ALDH1A1 (0.34) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7924679 | 0.88 | TAAR1 (0.35) | F2RHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL7923388 | 0.83 | CYP1A2 (0.36) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL12203757 | 0.82 | SMN1; SMN2 (0.37) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL12203758 | 0.82 | SMN1; SMN2 (0.37) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL12203761 | 0.82 | SMN1; SMN2 (0.37) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL7918297 | 0.80 | ROCK2 (0.39) | ALDH1A1MAPTTAAR1ADRA2ANPC1 | |
| SCHEMBL7919982 | 0.77 | TAAR1 (0.42) | TAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |