Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 3/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921745 | 0.88 | F2R (0.38) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL7911135 | 0.87 | ALDH1A1 (0.34) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL7924679 | 0.86 | TAAR1 (0.35) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL12230553 | 0.81 | HPGD (0.39) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL7923388 | 0.77 | CYP1A2 (0.36) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL12203758 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL12203761 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL12203757 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL7918297 | 0.70 | ROCK2 (0.39) | ALDH1A1TAAR1ADRA2ANPC1RAB9A | |
| SCHEMBL12203754 | 0.70 | KDM4E (0.35) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |