SCHEMBL7921871

SCHEMBL7921871

CCOC(=O)C(F)(CC(I)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.33
MMP8 P22894 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921940 0.86 MAPT (0.34) POLBMAPTKDM4EKMT2AMMP8
SCHEMBL7928035 0.85 POLB (0.33) POLBMAPTKDM4EKMT2AMMP8
SCHEMBL7928041 0.71 MAPT (0.36) POLBMAPTKDM4EKMT2ANPSR1
SCHEMBL12555642 0.70 POLB (0.44) POLBMAPTKDM4EKMT2ANPSR1
SCHEMBL7933881 0.70 TSHR (0.35) POLBMAPTKDM4EKMT2AMMP8
SCHEMBL2050077 0.69 CA1 (0.43) POLBMAPTKDM4EKMT2ANPSR1
SCHEMBL2691616 0.68 THRB (0.46) POLBMAPTKDM4EKMT2ANPSR1
SCHEMBL197278 0.68 THRB (0.46) POLBMAPTKDM4EKMT2ANPSR1
SCHEMBL3861059 0.68 THRB (0.46) POLBMAPTKDM4EKMT2ANPSR1
SCHEMBL5704701 0.68 THRB (0.46) POLBMAPTKDM4EKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0822175-B1 Hydrogen-containing fluorosurfactant and its use in polymerisation DU PONT (US) 2001-05-16 EP disclosed
US-5763552-A Hydrogen-containing flourosurfacant and its use in polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-09 US disclosed
EP-0822175-A2 Hydrogen-containing fluorosurfactant and its use in polymerisation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-02-04 EP disclosed