Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CCR3 | P51677 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924002 | 0.86 | LMNA (0.59) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7924064 | 0.85 | LMNA (0.58) | MEN1KMT2ALMNAALDH1A1ADRA1D | |
| SCHEMBL7927378 | 0.85 | MEN1 (0.60) | MEN1KMT2ACCR3POLB | |
| SCHEMBL7927349 | 0.83 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1CCR3 | |
| SCHEMBL7924050 | 0.83 | MEN1 (0.50) | MEN1KMT2ACYP1A2LMNAALDH1A1 | |
| SCHEMBL7924082 | 0.82 | MEN1 (0.48) | MEN1KMT2AKDM4EALDH1A1CCR3 | |
| SCHEMBL7927342 | 0.82 | LMNA (0.49) | MEN1KMT2ALMNAALDH1A1CCR3 | |
| SCHEMBL7921904 | 0.81 | MEN1 (0.48) | MEN1KMT2AKDM4EALDH1A1CCR3 | |
| SCHEMBL7921621 | 0.81 | ALDH1A1 (0.76) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL7915455 | 0.76 | LMNA (0.58) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |